Abstract

Upper Limit of Normal Serum Alanine Transaminase ALT and Correlation with Gender and BMI

Alanine transaminase ALT and aspartate transaminase AST are considered as important marker for hepatocellular membrane damage, ALT is more ƐÆ?Ä?cŝĮc to hepatocellular injury than AST, once transaminases rise by 1-4% of the general Æ?ŽÆ?ƵůÄ?Æ?ŽnÍ? it is cůÄ?ƐƐŝĮÄ?Ä? according to upper limit of normal ULN to Mild when rise up to (2-3) Æ?mÄ?Ɛ of ULN such as in celiac disease, thyroid disease (hypo or hyperthyroidism), adrenal ŝnƐƵĸcŝÄ?ncyÍ? systemic ŝnĨÄ?cÆ?ŽnƐÍ? etc. Moderate when rise from 2-3 Æ?mÄ?Ɛ to 20 Æ?mÄ?Ɛ of ULN such as in the early stages of viral Å?Ä?Æ?Ä?Æ?Æ?ƐÍ? cŽnŐÄ?ƐÆ?vÄ? hepatopathy and non- alcoholic ĨÄ?Æ©y live disease NAFLD that accounts the most common cause of mild to moderate Ä?ůÄ?vÄ?Æ?Žn ALT in Ä?ƐymÆ?Æ?ŽmÄ?Æ?c Æ?Ä?Æ?Ä?nÆ?ƐÍ? Severe when rise more than 20 Æ?mÄ?Ɛ of UNL such as in acute viral Å?Ä?Æ?Ä?Æ?Æ?ƐÍ? ischemic Å?Ä?Æ?Ä?Æ?Æ?Ɛ and drug induced Å?Ä?Æ?Ä?Æ?Æ?Ɛ


Author(s):

Zyad Alali



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